SELUTION 4 De Novo Small Vessel IDE Trial
Prospective, randomized controlled, single-blind, multicenter, clinical trial to demonstrate
the safety and efficacy of the SELUTION SLR 014 PTCA DEB for treatment of de novo lesions in
small coronary vessels, defined as reference vessel diameter (RVD) of 2.00 mm to...
Age: 18 years - 66+
Gender: All
Imaging Coronary Microvascular Dysfunction (CMD) Study
Angina is a common clinical symptom of ischemic heart disease, affecting up to 11 million
people in the United States alone, and 112 million people globally. Despite this, 4 in 10
patients undergoing elective coronary angiography for angina and ischemia do not have
...
Age: 18 years - 66+
Gender: All
The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
The aim of the prospective randomized single center study is to evaluate the effect of a
short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease
(CVD) risk factors in patients with CVD.
Age: 18 - 80 years
Gender: All
Mammography and Breast Arterial Calcification: An Information-Sharing Trial
The purpose of this research study is to determine the potential benefits of adding
information on patients' breast arterial calcification (BAC) results to the standard results
letter women receive after mammography. In addition to looking for potential breast cance...
Age: 40 years - 66+
Gender: Female
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant
coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty
about the benefits and the optimal timing of revascularization for such patients. There ...
Age: Birth - 66+
Gender: All
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will
improve clinical outcomes and quality of life (QOL) compared to single arterial grfating
(SAG).
The specific aims of ROMA:Women are:
Aim 1: Determine the impact of ...
Age: 18 years - 66+
Gender: Female
XIENCE 28 USA Study
The XIENCE 28 USA Study is prospective, single arm, multi-center, open label, non-randomized trial to evaluate safety of 1-month (as short as 28 days) dual antiplatelet therapy (DAPT) in subjects at high risk of bleeding (HBR) undergoing percutaneous coronary interventi...
Age: 18 - 100 years
Gender: All
A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease
The goal of this study is to find out if a drug called ACT-246475 can prevent platelets from
binding together when administered by an injection under the skin in the thigh or in the
belly. Another goal is to know how fast and for how long ACT-246475 works and if there...
Age: 18 - 85 years
Gender: All
Supporting Patients Undergoing HIgh-Risk PCI Using a High-Flow PErcutaneous Left Ventricular Support Device (SHIELD II)
The HeartMate PHP System is a temporary (<6 hours) ventricular assist device indicated for
use during high-risk percutaneous coronary interventions (PCI) performed electively or
urgently in hemodynamically stable patients with severe coronary artery disease, when a he...
Age: 18 - 100 years
Gender: All